05-03-2018

High performance liquid chromatography (HPLC) and, increasingly, ultra-high performance liquid chromatography (UHPLC) are the analytical workhorses of the pharmaceutical industry. All stages of the product's lifecycle, from early development until production and stability testing needs chromatographic analysis to characterize and quantify target molecules. 

This application notebook compiles more than twenty application notes covering important aspects of biopharmaceutical analysis such as protein aggregation, charge isoforms and glycosylation as well as determination of drug-to-antibody ratio (DAR) of ADCs. The last section of the notebook provides tips and tricks to improve chromatographic separation of biomolecueles. 

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